Perinatal Outcomes of Magnesium sulphate and Diazepam use in Severe Pre-eclamptic and Eclamptic Mothers, Jimma University Specialized Hospital, Southwest Ethiopia

Authors

  • Gizat Molla Kassie Jimma University
  • Dereje Negussie Jimma University
  • Jemal Hussein Jimma University

Keywords:

Magnesium sulphate, diazepam, Severe pre-eclampsia, Eclampsia, perinatal outcome

Abstract

Currently the preferred anticonvulsant used to treat and prevent fits in eclampsia is magnesium sulphate. The main objective of this study was to evaluate the perinatal outcomes of magnesium sulphate and diazepam use in the management of severe pre-eclampsia and eclampsia in Jimma University Specialized Hospital. A retrospective hospital based cross-sectional comparative study was conducted using data collection format. Data was collected from the hospital delivery care register and patient chart records of all mothers who presented with the diagnosis of severe pre-eclampsia and eclampsia in two years and three months period from January, 2010 to April, 2012.

Descriptive analysis such as frequency and percentage, Chi-square test, binary logistic regression and non parametric tests were analyzed by SPSS version 16.0. A P-value of <0.05 was considered statistically significant in all tests.

A total data of 343 births were included in this study. Two hundred seventeen from magnesium sulphate and one hundred forty from diazepam treated mothers group, were reviewed and analyzed.

Author Biographies

Gizat Molla Kassie, Jimma University

Clinical Pharmacist and Lecturer, Department of Pharmacy, College of Public Health and Medical Sciences, Jimma University, Ethiopia

Dereje Negussie, Jimma University

Consultant Obstetrician and Gynecologist , Department of Gynecology and obstetrics, College of Public Health and Medical Science, Jimma University, Ethiopia

Jemal Hussein, Jimma University

Assistant professor of Medicinal Chemistry, PhD scholar,

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Published

2014-03-26

How to Cite

Kassie, G. M., Negussie, D., & Hussein, J. (2014). Perinatal Outcomes of Magnesium sulphate and Diazepam use in Severe Pre-eclamptic and Eclamptic Mothers, Jimma University Specialized Hospital, Southwest Ethiopia. International Journal of Sciences: Basic and Applied Research (IJSBAR), 13(1), 426–436. Retrieved from https://www.gssrr.org/index.php/JournalOfBasicAndApplied/article/view/1879

Issue

Vol. 13 No. 1 (2014)

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Articles

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