Effect of Intrathecal Labor Analgesia (ILA) in Normal Labor Study on the Dynamics of Pain Intensity and Level of Prostaglandin (PGE2) Maternal Plasma

Abstract

After 5 minutes of ILA placement and ILA group VAS (2.1/2.2) lower than non ILA group (7.6/6.9). At the time of fully dilated cervix (stage II) in ILA group VAS (1.8/3.7) much lower than non ILA group (7.7/7.2). All the previous result is statistically significant (P 0.001). Prostaglandin Level. In nuripara prostaglandin level in ILA group after 5 minutes ILA placement were lower than non ILA group but in multipara prostaglandin level total were lower in ILA group compared to non ILA. In conclusions, Painless labour using intrathechal analgesia (ILA) is a safe choice for parturient women with low pain tolerance. Therefore, this will have reducing tissue damage for birth canal.

The aim of the study is to examine the dynamics of pain intensity and level of prostaglandine maternal plasma in painless labour using intratechal labour analgesia. Methods of this study used a prospective cohort study of 77 parturient delivered in Bintaro Hospital and Archa Medika Hospital, Jakarta Indonesia was performed from January to June 2015. Parturient women chose whether they preferred painless labour using ILA to normal delivery without analgesia (NDWA). Fentanly 25 ug, bupivacaine 2,5 mg and clonidine 0,045 ug were administered through intrathecal as ILA. Pain intensity was recorded by the parturient on a visual analogue scale. Level of prostaglandine measured in 4 consecutive time. Obstetric parameters were followed and recorded, Apgar score were noted, and all the results were compared in the two groups.