Serological Survey for Hepadnavirus in Long-tailed Macaques (Macaca fascicularis) at their ex-situ Habitats in Indonesia

Authors

  • Intan Citraningputri Primatology, Graduate School of Bogor Agricultural University, Dramaga Bogor, Indonesia
  • Diah Iskandriati Primate Research Center, Bogor Agricultural University, Jalan Lodaya II no 5 Bogor 16151, Indonesia
  • Rachmitasari Noviana Primate Research Center, Bogor Agricultural University, Jalan Lodaya II no 5 Bogor 16151, Indonesia
  • Uus Saepuloh Primate Research Center, Bogor Agricultural University, Jalan Lodaya II no 5 Bogor 16151, Indonesia
  • R P Agus Lelana Faculty of Veterinary Medicine, Bogor Agricultural University, Dramaga Bogor, Indonesia
  • Joko Pamungkas Primate Research Center, Bogor Agricultural University, Jalan Lodaya II no 5 Bogor 16151, Indonesia Faculty of Veterinary Medicine, Bogor Agricultural University, Dramaga Bogor, Indonesia

Keywords:

hepatitis B virus, long-tailed macaques, ex-situ habitat.

Abstract

The discovery of hepatitis B virus (HBV) infection among long-tailed macaques from Mauritus Island in 2013 is a new finding that showed HBV could infect non-human primate family Cercopithecidae. The aim of this study is to investigate the prevalence of Hepadnavirus among Macaca fascicularis that are living outside of their natural habitat in Indonesia. Hepatitis B surface antigen (HBsAg) screening test was performed on 95 plasma and serum samples collected from the different sources captivity, confiscated long-tailed macaques, and performance monkey. DNA detection was carried out on seropositive samples to HBsAg. Screening test showed that 11 of 95 (11.6%) samples were reactive to HBsAg. Prevalence of HBsAg is higher in confiscated animals and performance monkey (55%) compared with captive M. fascicularis (45%). However, no HBV DNA could be detected in HBsAg samples that were tested. HBsAg positive result indicate that the long-tailed macaques could be infected by hepatitis B virus naturally, although HBV DNA could not be detected in this study.

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Published

2017-06-20

How to Cite

Citraningputri, I., Iskandriati, D., Noviana, R., Saepuloh, U., Lelana, R. P. A., & Pamungkas, J. (2017). Serological Survey for Hepadnavirus in Long-tailed Macaques (Macaca fascicularis) at their ex-situ Habitats in Indonesia. International Journal of Sciences: Basic and Applied Research (IJSBAR), 34(1), 268–275. Retrieved from https://www.gssrr.org/index.php/JournalOfBasicAndApplied/article/view/6266

Issue

Vol. 34 No. 1 (2017)

Section

Articles

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