Green Chemistry and Biginelli Reaction

Authors

  • Hind Abderhman Elmusharaf Chemistry Department, College of Science, Sudan Unversity of Science and Technology, Khartoum, Sudan.
  • Ahmed E. M. Saeed Chemistry Department, College of Science, Sudan Unversity of Science and Technology, Khartoum, Sudan.

Keywords:

Green chemistry, Biginelli, reaction.

Abstract

Synthesis of some 5-acetyl-6-methyl-4-aryl-3,4-dihydropyrimidne-2-one, 5-acetyl-6-methyl-4-aryl-3,4- dihydropyrimidne-2-thione, 5-ethoxycarbonyl-6-methyl-4-aryl-3,4-dihydropyrimidine-2-one and 5- ethoxycarbonyl-6-methyl-4-aryl-3,4-dihydropyrimidine-2-thione by green chemistry methods without catalysis and without solvent, the reaction progress was followed by TLC analysis and the chemical structure confirmed by spectroscopic analysis (UV, IR and

References

Paul T. Anastas & John C.Warner.?Green Chemistry: theory and practice? published in United states by Oxford University Press Inc., New York. (1998) P.6-8.

Mike Lancaster. ?Green Chemistry: An Introductory Text? Published by The Royal Society of Chemistry, Thomas Graham House, Science Park, Milton Road, Cambridge CB4 0WF,UK.(2002).P.5.

Kappe. C.O. ?Recent advances in the Biginelli dihydropyrimidine synthesis-new tricks from an old Dog? Acc. Chem. Res. 33(2000) 879-888.

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Published

2017-04-26

How to Cite

Elmusharaf, H. A., & E. M. Saeed, A. (2017). Green Chemistry and Biginelli Reaction. International Journal of Sciences: Basic and Applied Research (IJSBAR), 33(1), 15–20. Retrieved from https://www.gssrr.org/index.php/JournalOfBasicAndApplied/article/view/7181

Issue

Vol. 33 No. 1 (2017)

Section

Articles

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