Rapid Plasma Reagin (RPR) Inspection in Pulmonary Tuberculosis Patients
Keywords:
Syphilis, Tuberculosis, Rapid Plasma Reagin.Abstract
Rapid Plasma Reagin (RPR) is one method of non-treponemal examination for the diagnosis of syphilis by detecting non-specific antibodies (reagin) in syphilis suspect blood. Rapid Plasma Reagin examination was performed using immunoassay method. In this immunoassay method is done with agglutination, namely antigen and antibody ties in the patient serum. In patients with tuberculosis is predicted to have non-specific antibodies (reagin) in their serum. This is because the immune response is a hypersensitivity reaction type IV or slow type. This study aims to determine the results of Rapid Plasma Reagin examination in patients with pulmonary tuberculosis. This research is a laboratory observation conducted on 30 samples of patients with pulmonary tuberculosis. Samples were obtained from several hospitals and health centers in Makassar. The specimens test were conducted at the Laboratory of Health Analyst Department of Health Polytechnic of Ministry of Health Makassar in April 2017. The results were obtained from Rapid Plasma Reagin examination, strong reactive of 5 specimens (16.67%), weak reactive of 25 specimens (83.33%) of 30 serum samples of patients with pulmonary tuberculosis. Conclusion, Rapid Plasma Reagin is reactive in patients with pulmonary tuberculosis. This occurs because of the presence of non-specific antibody (reagin) in the serum of patients with pulmonary tuberculosis with cardiolipin antigen used. Accordingly, in order to establish the diagnosis of syphilis in patients, it is necessary to conduct more specific confirmatory examinations to reduce the likelihood of biologically false positive results.
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