The Effect of Donor Blood Storage Time to the Counts of Erythrocyte and Thrombocyte

Authors

  • Nurlia Naim Department of Health Analyst, Health Polytechnic, Ministry of Health Makassar
  • Muhammad Nasir

Keywords:

Transfusion, Storage, Erythrocytes, Thrombocyte.

Abstract

Blood transfusion is a process of transferring blood from donator to recipient that serves to improve the condition of anemia by using good quality blood and the amount needed. It is done by giving erythrocytes or blood component as needed. Until now, the effect of storage time on erythrocyte and thrombocyte stability is not known clearly. This research aims to determine the effect of storage time on blood and how large the effect of donor blood storage time to erythrocytes and thrombocyte counts. The research is quasy experiment with time series design modification or Time Series Design and Non Randomized Pretest-Postest Control Group. The sample of this research is blood donor (whole blood) blood group A, B, and O. Data analysis was used One Way Anova test (? = 0,05). In the amount of erythrocytes obtained F. Count (0.14) <F. table (5.14), which means there is no effect of donor blood storage time on the amount of erythrocytes. For platelets in the F. Count (426,2)> F. table (5.14), which means there is an influence between the number of platelets in the blood before being stored with the number of platelets stored for 1 week and 2 weeks. Advice for Indonesian Red Cross institutions to provide a tool for hematological examination as one of the preliminary tests of donor blood before donating to recipients.

References

Bermawi, H. Transfusi Darah dan Komponen Darah.In: M. S. Kosim, et al.eds. Buku Ajar Neonatologi. 1ed.s.l: Ikatan Dokter Anak Indonesia, 2010. p. 285.

Erviana I. Pengaruh Waktu Penyimpanan Darah Donor Terhadap Jumlah Leukosit Metode Konvensional.Makassar: Analis Kesehatan. 2011.

Vaught JB, Henderson MK, Compton CC. Biospecimens and biorepositories: from afterthought to science. Cancer Epidemiol Biomarkers Prev. 2012;21:253–255. [PMC free article] [PubMed]

Campbell LD, Betsou F, Leiolani Garcia D, Giri JG, Pitt KE, Pugh RS, Sexton KC, Skubitz AP, Somiari SB. Development of the ISBER Best Practices for Repositories: Collection, Storage, Retrieval and Distribution of Biological Materials for Research. Biopreservation and Biobanking. 2012;10:232–233.[PubMed].

National Cancer Institute Best Practices for Biospecimen Resources. [Accessed October 21, 2013];http://biospecimens.cancer.gov/bestpractices/2011-NCIBestPractices.pdf.

Departemen Kesehatan Republik Indonesia,. Hematologi.Jakarta: Pusdiknes Depkes RI. 1989

Dumont LJ, AuBuchon JP. Evaluation of proposed FDA criteria for the evaluation of radiolabeled red cell recovery trials. Transfusion. 2008 Jun;48(6):1053–60. [PubMed].

Dumont LJ, AuBuchon JP, Gulliksson H, et al. In vitro pH effects on in vivo recovery and survival of platelets: an analysis by the BEST Collaborative. Transfusion. 2006;46(8):1300–5. [PubMed].

Gandasoebrata R. Penuntun Laboratorium Klinik. Jakarta: Dian Rakyat.1969.

Hoffbrand A.V, Pettit J.E, Moss P.A.H. Kapita Selekta Hematologi. Jakarta: EGC. 2005.

Latief. Transfusi Darah. In: R. Hassan & H. Alatas , eds.Buku Kuliah 1 Ilmu Kesihatan Anak. Jakarta: Bagian Ilmu Kesehatan Anak Fakultas Kedokteran. Universitas Indonesia, 2007.p. 483.

Chandra, S. Transfusi Darah dan Infus Cairan. In: T.Rachimhadhi, G.H.Wiknjosastro & A. B. [13] Saifuddin, eds.Ilmu Kebidanan. Jakarta: Yayasan Bina Pustaka Sarwono Prawirohardjo, 201.p.419.

Sherwood L. Fisiologi Manusia dari Sel ke Sistem, Edisi 2. Jakarta;EGC. 2001.

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Published

2018-07-13

How to Cite

Naim, N., & Nasir, M. (2018). The Effect of Donor Blood Storage Time to the Counts of Erythrocyte and Thrombocyte. International Journal of Sciences: Basic and Applied Research (IJSBAR), 40(1), 120–127. Retrieved from https://www.gssrr.org/index.php/JournalOfBasicAndApplied/article/view/9097

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