Antioxidant and Anti-diabetic Properties of Bitter Gourd (Momordica charantia) Fruit
Keywords:Momordica charantia, antioxidant, glucose uptake, acarbose, insulin
This study aimed to determine the therapeutic values of local bitter gourd relative to the conventional drugs, especially in managing oxidative stress and blood glucose. The therapeutic values of bitter gourd fruit were evaluated using three antioxidant assays (2,2-diphenyl-1-picrylhydrazyl scavenging system [DPPH], the ability of ferric ion reduction in plasma [FRAP], total phenolic content [TPC]) and three hyperglycemic assays (inhibition of ?-amylase and ?-glucosidase and glucose uptake by human carcinoma liver cell [HepG2]). The result showed that bitter gourd fruit is not only a powerful secondary antioxidant but also a potent anti-diabetic food, which supported the use of bitter gourd fruit in suppressing high blood sugar in traditional medicine.
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