Development of Tupaia javanica Immortal Hepatocytes Culture for Javan Gibbon Hepatitis B Virus Replication
Keywords:
Immortal hepatocytess culture, Tupaia javanica, Javan gibbon HBV.Abstract
Hepatitis B is a liver inflammation caused by hepatitis B virus (HBV). Hepatocytes culture is an in vitro model widely used to study various physiological and pathological aspects of HBV. Referring to 3R principles (Reduction, Refinement, Replacement), it is important to minimize the use of animals in research (in this study :Tupaia).
References
World Health Organization. Hepatitis B vaccines. Weekly Epidemiological Record 40:405-420.Internet:www.who.int/wer/2009/wer8440.pdf>. 2009 [20 July 2015].
World Health Organization. Manual for The Development and Assesment of National Viral Hepatitis Plans. <http://apps.who.int/iris/bitstream/10665/183726/1/9789241509350_eng.pdf?ua=1>. 2015. [ 20 October 2015].
Guha C, Mohan S, Chowdhury MR, Chowdhury JR. 2004. Cell culture and animal models of viral hepatitis. Part 1: Hepatitis B. Lab Anim. 33 (7): 37-46.
Han KH, Duckworth JW, Molur S. 2008. Tupaia belangeri. The IUCN Red List of Threatened Species2008: e.T41492A10468101. <http://dx.doi.org/10.2305/IUCN.UK.2008.RLTS.T41492A10468101.en> .[19 October 2015].
Galle PR, Hagelstein J, Kommerell B, Volkmann M, Schranz P, Zentgraf H. 1994. In vitro experimental infection of primary human hepatocytesss with hepatitis B virus.Gastroentology. 106:664-673.
Walter E, Keist R, Niedero ST B, Pult I, Blum HE. 1996. Hepatitis B virus infection of Tupaiahepatocytesss in vitro and in vivo. Hepatology 24(1):1-5.
Kock J, Nassal M, MacNelly S, Baumert TF, Blum HE, Weizsacker FV. 2001. Efficient infection of primary Tupaiahepatocytesss with purified human and wolly monkey hepatitis B virus. J Virol. 75 (11): 5084-5089.
Cao J, Yang EB, Su JJ, Li Y, Chow P. 2003. The tree shrews:, adjuncts and alternatives to primates as models for biomedical research. J Med Primatol. 32: 123-130.
Han KH, Maharadatunkamsi D. 2008.Tupaia javanica. The IUCN Red List of Threatened Species 2008: e.T41496A10469813. <http://dx.doi.org/10.2305/IUCN.UK.2008.RLTS.T41496A10469813.en>
October 2015].
Glebe D, Aliakbari M, Krass P, Knoop EV, Valerius KP, Gerlich WH. 2003. Pre-S1 antigen-dependent infection of Tupaiahepatocytess cultures with human hepatitis B virus. J Virol. 77(17): 9511-9521.
Warren KS, Heeney JL, Swan RA, Heriyanto, Verschoor EJ. 1999. A new group of Hepadnaviruses naturally infecting orangutans (Pongo pygmaeus). J Virol 73(9):7860-7865.
Purwaningsih E. 2010. Telomer, aging dan karsinogenesis. Jurnal Kedokteran Yarsi 18 (2) : 137-143.
Landon, Kirk A. 2005. Telomerase and Cancer. Mol Cancer Res 2005;3(9).
Downloads
Published
How to Cite
Issue
Section
License
Authors who submit papers with this journal agree to the following terms.