Evaluation of the Potential Neurotoxicity of Gold Nanoparticles in the Different Rat Brain Regions


  • Neveen A. Noor Zoology Department, Faculty of Science, Cairo University, Egypt
  • Heba M. Fahmy Biophysics Department, Faculty of Science, Cairo University, Egypt
  • Iman M Mourad Zoology Department, Faculty of Science, Cairo University, Egypt


nanoparticles, oxidative stress, AChE, brain, rat.


The present study aims to investigate the potential adverse effects of gold nanoparticles (Au NPs) in the cortex, hippocampus, striatum, midbrain, cerebellum and medulla of adult male Wistar rat through the estimation of some oxidative stress parameters and acetylcholinesterase (AChE) activity. Rats were divided into two main experimental groups. Animals of the 1st and 2nd groups were intraperitoneally injected with a single dose (100


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How to Cite

A. Noor, N., M. Fahmy, H., & M Mourad, I. (2016). Evaluation of the Potential Neurotoxicity of Gold Nanoparticles in the Different Rat Brain Regions. International Journal of Sciences: Basic and Applied Research (IJSBAR), 30(5), 114–129. Retrieved from https://www.gssrr.org/index.php/JournalOfBasicAndApplied/article/view/6641