The Effectiveness of Extract Snack Head Fish and Virgin Coconut Oil (VCO) on Sputum Conversion and Levels of Interferon-? in Patients with Pulmonary TB Multi Drug Resistant (MDR) in Labuang Baji Hospital Makassar

Authors

  • Freddy Chandra Montolalu Postgraduate Doctoral Program, Postgraduate School of Hasanuddin University, Makassar
  • Veni Hadju Nutritional Sciences Study Program, Faculty of Public Health, Hasanuddin University Makassar
  • Gatot S.Lawrence Pathology Department, Medical Faculty of Hasanuddin University, Makassar
  • Siti Wahyuni Anatomy Department , Faculty of Medicine, Hasanuddin University Makassar
  • Maryunis Maryunis General Hospital of Dr. Wahidin Sudirohusodo Makassar, Nursing Science Study Program, Indonesian Muslim University

Keywords:

MDR Pulmonary TB, VCO, cork fish albumin capsule, albumin, interferon gamma.

Abstract

Background: Treatment of pulmonary MDR TB disease is relatively very expensive and takes a long time to heal, This study aims to determine the effect of treatment DOTS-Plus capsules supplemented catfish albumin protein coupled VCO can affect the conversion of sputum smear and levels of interferon-? in pulmonary MDR TB patients who received treatment DOTS-Plus in Labuang Baji Hospital, Makassar. This study is a quantitative study with randomized controlled quasi-experimental approach with a sample size of 30 people (15 experimental, 15 control). Data analysis was done using the Independent Sample T Test with a confidence level of 95%. All the data were Analyzed by SPSS software, version 21.0 (SPSS, Inc., Chicago, IL).

Results: All the groups in which I no conversion. The intervention began in the second conversion of 80% and all had more conversions in III. Control in II started there is a conversion of 53.3% and until VI there are still 3.3% which is not convertible. The average levels of interferon gamma first month (intervention: 153.26

References

WHO.2013.Definitions and reporting framework for tuberculosis .revision. Geneva, Switzerland, 2013

WHO, 2014.

Depkes RI.2007.

Depkes RI. 2008.

Khariroh., Syamilatul, 2006.FactorRisikoKegagalanKonversi Pasien Tuberkulosis Paru Program Pengobatan DOTS FaseIntensif DiRumah Sakit DR SOETOMO Dan PencegahanPenyakitDanBadan Pengendalian (BP4) Karang Tembok Surabaya.Program Pasca Sarjana Universitas Airlangga.

Subowo.2010.

Eric. C. Leung et.al. 2010. Treatment Outcomes of Multidrug-Resistant Tuberculosis (MDR-TB) and Extensively Drug-Resistant Tuberculosis (-TB) in Hong Kong.

Chandra, R.K. and Bloom. 1996.

Widjaja, J.T., Jasaputra, D.K., Roostati, R.L. 2010. Analisis Kadar Interferon Gamma pada Pasien Tuberkulosis Paru dan Orang Sehat. Journal Respirology Indonesia.Vol.30.No 2:119-123.

Taslim, NA. dkk., 2005.

Taslim, NA.,2006.

Rotor, A.V. 2008.Glycerol Monolaurat (GML) in Virgin Coconut Oil Destroys Tuberculosis Bacteria. Multi Disciplinary Research Journal of the UST Graduate School.Volume 8.Number 1.Manila Filipina.

Ashitani, J.I., Matsumoto.N, Nakazato.M, 2009.Effect of octanoid acid-rich formula on plasma ghrelin level in cachectic patients with chronic respiratory disease.Licensee BioMed Central Ltd.Japan.

Zakaria, A., Somchit, M.N., Mat.J.2011.In vivo antinoceptive and anti inflamatory activities of dried and fermented processed virgin cocnut oil.Med Princ Pract;20(3):231-6.

Arifin, M., Hadju, V., Astuti, N., & Wahyuni, S. (2014). Supplements Effects of Virgin Coconut Oil and Albumin Capsules (Catfish protein) on TB Patients Receiving Multi Drugs Therapy-DOTS Strategic in BBKPM Makassar, Indonesia. International Journal of Scientific and Research Publications , 1-6.

Ahmad,Z., dkk,2007.Peran Vitamin D3 Dalam Sistem Imun Pasien Tuberkulosis Paru.Program Pendidikan Dokter Spesialis Ilmu Penyakit Dalam FK UNSRI/RSMH Palembang.

Ahmad, S. 2011.

McMurray DN., Bartow R.A., Mintzer C.L., Hernandez-Frontera E.1990. Micronutrient status and immune function in tuberculosis. Ann N Y Acad Sci;587:59-69

Diekema, D.J., Villamor E et al. 2008.Nutritional Supplementation and TB Treatment. Journal Infect Dis. 1.

Fife, Bruce, C.N., N.D, 2004.Coconut Oil Miracle, Cetakan kedua, PT Bhuana Ilmu Populer, Jakarta 1114.

Dalmacion,J. 2011.

Handajani, N.S., Dharmawan, R. 2009.

Farah, Julia Nasution. 2009. Peranan Virgin Coconut Oil (VCO) Dalam Menyembuhkan Lesi Oral Pasien HIV/AIDS. Skripsi. Fakultas Kedokteran Gigi Universitas Sumatera Utara Medan.

Malle.J. 2008.

Pottumarthy S, Morris AJ, Harrison AC, Wells VC.1999. Evaluation of the tuberculin gamma interferon assay: potential to replace the Mantoux skin test. J Clin Microbiol; 37:3229-32.

Wen-Lin S, Wann-Cherng P, dkk. 2009.Association of Reduced Tumor Necrosis Factor Alpha, Gamma Interferon, and Interleukin-113 (IL-113) but Increased IL-10Expression with Improved Chest Radiography in Patients with Pulmonary Tuberculosis.American Society for Microbiology.Vol.17,No. 2.CLINICAL AND VACCINE IMMUNOLOGY, Feb. 2010, p. 223

Su, W L., Perng, W C., Huang, C H., Yang, C Y., Wu, C P., Chen, J H.2010.

Widjaja, J.T., Jasaputra, D.K., Roostati, R.L. 2010. Analisis Kadar Interferon Gamma pada Pasien Tuberkulosis Paru dan Orang Sehat. Journal Respirology Indonesia.Vol.30.No 2:119-123.

Rumende, C.M., Sukmana, N., Suwondo, Amin, Z., Sibuea, W.H.

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Published

2016-12-01

How to Cite

Montolalu, F. C., Hadju, V., S.Lawrence, G., Wahyuni, S., & Maryunis, M. (2016). The Effectiveness of Extract Snack Head Fish and Virgin Coconut Oil (VCO) on Sputum Conversion and Levels of Interferon-? in Patients with Pulmonary TB Multi Drug Resistant (MDR) in Labuang Baji Hospital Makassar. International Journal of Sciences: Basic and Applied Research (IJSBAR), 30(4), 147–158. Retrieved from https://www.gssrr.org/index.php/JournalOfBasicAndApplied/article/view/6642

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