Analysis of Serum Creatinine Level and Contrast Volume in Contrast Induced Nephrophaty Incidence after Percutaneus Coronary Intervention

Authors

  • Yuyun Widaningsih Department of Clinical Pathology, Hasanuddin University, Makassar, Indonesia
  • Rosdiana Natsir Department of Biochemistry, Hasanuddin University, Makassar, Indonesia
  • Mansyur Arif Department of Clinical Pathology, Hasanuddin University, Makassar, Indonesia
  • Uleng Bahrun Department of Clinical Pathology, Hasanuddin University, Makassar, Indonesia
  • Hasyim Kasim Internal Medicine Department , Hasanuddin University, Makassar, Indonesia
  • Fitriani Mangerangi Department of Clinical Pathology, Hasanuddin University, Makassar, Indonesia
  • Nursin Abdul Kadir Department of Clinical Pathology, Hasanuddin University, Makassar, Indonesia
  • Fitri Hamka Department of Clinical Pathology, Hasanuddin University, Makassar, Indonesia
  • Nadyah Haruna Medicine Faculty, UIN Alauddin University, Indonesia
  • Mochammad Hatta Department of Immunology and Biomolecular, Hasanuddin University, Makassar, Indonesia
  • Andi Nilawati Usman Halal Center, Public Health Hasanuddin University

Keywords:

Percutaneus Coronary Intervention (PCI, Contrast Induced Nephrophaty (CIN), Serum Creatinine, , Contrast Volume.

Abstract

The increase of percutaneous coronary intervention (PCI) in cardiovascular patients through the administration of contrast agents leads to a potential risk of contrast induced nephrophaty (CIN) incidence. This study aims to analyze the particular level of serum creatinine through the administration of contrast agents and specific contrast volumes in CIN incidence after PCI. The experimental design used in this study was cross sectional design. The total samples were 30 patients who underwent percutaneus coronary intervention (PCI) at the Cardiovascular Center Unit of Dr. Wahidin Sudirohusodo Hospital in Makassar Municipality.

The statistical test used to analyze serum creatinine levels before and after PCI was Mann-Whitney U test and contrast volumes were compared based on results of the analysis of serum creatinine levels. Results of the analysis of serum creatinine levels after PCI indicated that 10 patients (33.33%) experienced CIN incidence and their serum creatinine levels were higher than other remaining patients at the normal level of serum creatinine. The increase of serum creatinine levels before and after PCI showed statistically significant difference between the CIN group and the non-CIN group. On average, administration of contrast volumes at >50 mL and frequency of CIN incidence was found in diagnosed patients who experienced the coronary artery disease (CAD) at both grade 1 and 3. Results of this study proved that PCI increased potential risk of CIN incidence and provided a novel data to be used for the elucidation in subsequent health studies,

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Published

2017-04-14

How to Cite

Widaningsih, Y., Natsir, R., Arif, M., Bahrun, U., Kasim, H., Mangerangi, F., Kadir, N. A., Hamka, F., Haruna, N., Hatta, M., & Usman, A. N. (2017). Analysis of Serum Creatinine Level and Contrast Volume in Contrast Induced Nephrophaty Incidence after Percutaneus Coronary Intervention. International Journal of Sciences: Basic and Applied Research (IJSBAR), 32(3), 186–193. Retrieved from https://www.gssrr.org/index.php/JournalOfBasicAndApplied/article/view/7174

Issue

Vol. 32 No. 3 (2017)

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