Early Predictor of Functional Outcome for Acute Hemorrhagic Stroke. Study on ICH Score and Leucocytes Count

Abstract

Acute spontaneous intracerebral haemorrhage is often fatal, so that an accurate prediction of patient outcome is necessary for the patient's families and physician to make decisions for further handling. Assessment of functional outcome that is often used for stroke cases is Modified Rankin Scale, which can only be done clinically at months 3 , 6 , or 12 after the attack. Several attempts were made to predict functional outcome early. ICH Score was made to predict the outcome that can be done quickly and accurately which can be checked directly when patients came to the hospital . The role of inflammatory reactions in the pathophysiology of acute stroke hemorrhage began rising studied recently. Several clinical studies show a link between biomarkers of inflammatory reactions and the outcome  of the acute brain hemorrhage, but the relationship between serum biomarkers and functional outcomes among patients who survive has not been evaluated yet. Functional outcome assessment should be done as early as possible, because it can provide informations for management strategies or further managements of the patient, and in particular these would be useful for the patient's families and physician to predict the prognosis of patients.

Aim of the study to know the ICH score as clinical indicator and the count of leucocytes as an indicator of immunologic response in predicting 30-days functional outcome in patients with acute haemorrhagic stroke. The results of this study indicate the higher ICH score will worsen 30-days functional outcome. Normal early leukocytes count can be used to predict a good functional outcome in patients with acute hemorrhagic strokes.